A 5 MeV RFQ delivering a beam current up to 30 mA will be constructed and installed at the Laboratori Nazionali di Legnaro (LNL) in the next three years. This high intensity acceleartor will be mainly dedicated to neutron production for the generation of exotic nuclei and will be also used as the injector of a 100 MeV Drift Tube Linac which will be installed in the future at the LNL. Part of the beam delivered by the RFQ (1-2 mA) will be exploited for neutron production for BNCT of skin melanoma via the 9Be(p,n)9B or the 9Be(d,n)10B reaction. The thermal neutron irradiation field will be obtained with a moderating configuration based on the structure designed in the framework of the TERA program and under experimental verification at the LNL Van De Graaff accelerator. In the period necessary for the construction of the RFQ facility, the source characterisation, the development of a beam monitoring system and microdosimetric measurements wiil be performed at the experimental structure mentioned above. As the therapeutic dose (about 20 Gy from the 10B(n,a)7 Li reaction products) cannot be delivered at the LNL experimental structure (the Van De Graaff maximum current is 3 µA), radiobiology, phanton dosimetry (with TL and gel dosemeters) and animal irradiation will be performed at the BNCT facility of the TAPIRO reactor in C.R. Casaccia ENEA Centre near Rome (Italy). The facility will be available within this year and will provide a thermal and an epithermal collimated neutron filed (fluence rate about 6x108 cm-2 s-1) useful for skin melanoma and brain glioma irradiation in the framework of this experimental program.

The Experimental Program for BNCT Using a Fast Neutron Research Reactor (TAPIRO) and an Accelerator-Based Source

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1998-09-13

Abstract

A 5 MeV RFQ delivering a beam current up to 30 mA will be constructed and installed at the Laboratori Nazionali di Legnaro (LNL) in the next three years. This high intensity acceleartor will be mainly dedicated to neutron production for the generation of exotic nuclei and will be also used as the injector of a 100 MeV Drift Tube Linac which will be installed in the future at the LNL. Part of the beam delivered by the RFQ (1-2 mA) will be exploited for neutron production for BNCT of skin melanoma via the 9Be(p,n)9B or the 9Be(d,n)10B reaction. The thermal neutron irradiation field will be obtained with a moderating configuration based on the structure designed in the framework of the TERA program and under experimental verification at the LNL Van De Graaff accelerator. In the period necessary for the construction of the RFQ facility, the source characterisation, the development of a beam monitoring system and microdosimetric measurements wiil be performed at the experimental structure mentioned above. As the therapeutic dose (about 20 Gy from the 10B(n,a)7 Li reaction products) cannot be delivered at the LNL experimental structure (the Van De Graaff maximum current is 3 µA), radiobiology, phanton dosimetry (with TL and gel dosemeters) and animal irradiation will be performed at the BNCT facility of the TAPIRO reactor in C.R. Casaccia ENEA Centre near Rome (Italy). The facility will be available within this year and will provide a thermal and an epithermal collimated neutron filed (fluence rate about 6x108 cm-2 s-1) useful for skin melanoma and brain glioma irradiation in the framework of this experimental program.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/20.500.12079/3922
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