Modern management of Industrial Areas (IAs) can give an important contribution to Sustainable Consumption and Production (SCP) policy in Mediterranean regions. It includes activities related to environmental performance and sustainability, as well as marketing and promotion of the image of the Area and can allow to identify and exploit synergies among the settled companies to improve the overall efficiency in the use of natural resources of the area. Modern management is nevertheless a complex duty which comprises several tasks and requires a remarkable expertise in several fields. To help managers in performing these new tasks, a Mediterranean model, based on several project expe- riences realized at European and national level has been developed. The management model con- sists in a series of necessary steps to be followed to progress towards a more sustainable production system. To increase its effectiveness the model has been integrated with a set of web-based tools de- veloped in some European projects which address several aspects of IAs management: a checklist with a scoring system for evaluating and benchmarking at international level the initial status of an IAs; a database of best practices which can be adopted in Mediterranean IAs for improving their environ- mental, social and economic profile; a guide for designing and constructing eco-efficient industrial buildings; a software for calculating the carbon footprint of waste management in IAs; a checklist for logistic services to identify and to provide a set of practical steps that can be taken to successfully ac- complish a sustainable logistic service. In this paper, after outlining some characteristic of the production system of Mediterranean region and the weak points of the actual SCP, the tools developed for supporting a modern management of IAs are described and their contribution to SCP policies are discussed. Some suggestion for improving the national and local policies in Mediterranean area are then discussed in the conclusions.