This paper reports on the development of a lab-on-chip system for detection of DNA through the [Ru(phen)2(dppz)]2+ fluorescent intercalating dye. The device includes on the same glass substrate amorphous silicon photosensors, a thin film interferential filter and a microfluidic network based on polydimethylsiloxane. The suitability of the miniaturized system in detecting the fluorescence variation of the ruthenium complex, working as DNA intercalating molecules, is demonstrated.

Highly miniaturized system for on-chip detection of DNA

Tucci, M.
2016

Abstract

This paper reports on the development of a lab-on-chip system for detection of DNA through the [Ru(phen)2(dppz)]2+ fluorescent intercalating dye. The device includes on the same glass substrate amorphous silicon photosensors, a thin film interferential filter and a microfluidic network based on polydimethylsiloxane. The suitability of the miniaturized system in detecting the fluorescence variation of the ruthenium complex, working as DNA intercalating molecules, is demonstrated.
9780979806490
Ruthenium complex;Amorphous silicon photosensors;Lab-on-chip;Interferential filter
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/20.500.12079/5018
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