Operational indications and self-assessment checklist for internal audits in cyclotron facilities – an Italian experience

In this work the authors intend to provide useful operational indications to approach, with the best practice, the design of a cyclotron facility for the production of PET radioisotopes. Special attention is devoted to organizational and safety aspects. In order to prompt toward a systematic application of the proposed indications, the article presents them in form of a specific self-assessment checklist, consisting in a list of items which address the design process in all the different phases. This checklist represents a useful toolbox both in the design stage and subsequently for the development of internal audits.