Purpose: The aim of this study was to numerically and experimentally characterise the influence of tissues dimensions on the size and shape of microwave-induced ablation zones. Materials and methods: A 2.45GHz interstitial antenna was introduced into ex vivo bovine liver samples, delivering 60W for 10min; then the dimensions of the coagulated area were measured. Ablations were performed both in large samples (termed unrestricted tissue) for characterising the tissue response, and in thin samples, whose dimensions in the plane perpendicular to the antenna were smaller than the short axis of the ablated area obtained in unrestricted samples. In the numerical study the electromagnetic field emitted from the antenna and the corresponding temperature increase were evaluated in both unrestricted and thin tissue samples. Results: When the height of the tissue was smaller than the ablation diameter measured in unrestricted samples, a 7.5% increase in length of the ablated zone was experimentally observed. When both the height and width were lower than the diameter measured in unrestricted samples, an elongation of about 23.4% was experimentally obtained. The numerical study showed that the boundary conditions between the target tissue and the surrounding materials are critical. Conclusions: The ex vivo performances of microwave ablation devices are notably influenced by the shape and dimension of the tissues where the procedure takes place. Accordingly, dedicated interventional protocols should be developed for treatment planning on targets of different shape and size. © 2015 Informa UK Ltd. All rights reserved.
|Titolo:||Influence of the target tissue size on the shape of ex vivo microwave ablation zones|
|Data di pubblicazione:||2015|
|Appare nelle tipologie:||1.1 Articolo in rivista|